Search Result of "Sutthatip Markmee"

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ที่มา:วิทยาสารเกษตรศาสตร์ สาขา วิทยาศาสตร์

หัวเรื่อง:ไม่มีชื่อไทย (ชื่ออังกฤษ : Isolation of Anti-malarial Active Compound from Yanang (Tiliacora triandra Diels))

ผู้เขียน:ImgChalerm Saiin, ImgSutthatip Markmee

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Abstract

Malaria remains to be one of the serious problems in tropical countries because of the increase in antimalarial drug resistance. This investigation was to study the extraction of bioactive compounds with anti-malarial activity from Yanang (Tiliacora triandra Diels) root. The dried root was extracted with chloroform : methanol : ammonium hydroxide mixture (50:50:1). Further isolation and purification of the crude extract using column chromatography and crystallization techniques provided two pure alkaloid compounds: tiliacorinine (I) and tiliacorine (II) with 0.0082 and 0.0029 percent yield, respectively. Structures of I and II were confirmed by spectroscopy techniques and compared with reference data.

Article Info
Agriculture and Natural Resources -- formerly Kasetsart Journal (Natural Science), Volume 037, Issue 1, Jan 03 - Mar 03, Page 47 - 51 |  PDF |  Page