 ที่มา:วารสาร คณะสัตวแพทยศาสตร์หัวเรื่อง:ไม่มีชื่อไทย (ชื่ออังกฤษ : Effect of Tepoxalin on Fecal Cortisol Concentration in Rabbits after Ovariohysterectomy ) ผู้เขียน: Kritkrnda Kiratitana-olan, Chatchote Thitaram, Pinich Boontong, Raktham Maktrirat, Niyada Thitaram สื่อสิ่งพิมพ์:pdf AbstractDetermination of the analgesic efficacy of tepoxalin after ovariohysterectomy based on assessment of fecal cortisol cocentration was wtudied in 21 rabbits. Three studied groups ( 7 rabbits/group) consisted of : 1) placebo (oral administration of water 0.1 ml/kg); 2) tepoxalin - treated group I ( 10 mg/kg) ;and 3) tepoxalin - treated group II ( 20 mg/kg as an initial dose, followed by 10 mg/kg after 24 hr). Rabbits received placebo or tepoxalin orally 2 hr before and every 12 hr after surgery for 3 days. Feces were collected and analyzed pre-and post -operation. Te results showed fecal cortisol concentration in tepoxalin-treated group II were significantly lower than other groups. This study indicated that tepoxalin administration twice a day as an initial dose of 20 mg/kg. followed by 10 mg/kg after 24 hr affected the reduction of fecal cortisol concentration reflecting post-operation pain relief in rabbits. |