Search Result of "O. Lauhawinit"

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ที่มา:วิทยาสารเกษตรศาสตร์ สาขา วิทยาศาสตร์

หัวเรื่อง:ไม่มีชื่อไทย (ชื่ออังกฤษ : Study on Sulfadimethylpyrimidine in Pangasius pangasius Following the Intravenous, Intramuscular and Oral Drug Administration )

ผู้เขียน:ImgS. Sirivejapandu, ImgP. Chai-anan, ImgM. Limpoka, ImgW. Chuapoehuk, ImgU. Na-Nakorn, ImgO. Lauhawinit



The disposition of sulfadimethylpyrimidine was studied in Pangasius pangasius following the intravenous, intramuscular and oral drug dosing. The drug was administered as 25% solution at the dosage of 107.25 mglkg. Blood samples were collected via the caudal blood vessels at specific times and determined by the Direct and Total method of Bratton and Marshall. The drug was incompletely absorbed following intramuscular and oral administration. The bioavailability were 69.02% and 12.36% following the intramuscular and oral dosing, respectively. The Three Compartment Model would be used to describe the disposition of the drug in Pangasius pangasius. Estimation of all the rate constant was also obtained.

Article Info
Agriculture and Natural Resources -- formerly Kasetsart Journal (Natural Science), Volume 018, Issue 3, Sep 84 - Dec 84, Page 172 - 179 |  PDF |  Page