Search Result of "Niyada Thitaram"

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ที่มา:วารสาร คณะสัตวแพทยศาสตร์

หัวเรื่อง:ไม่มีชื่อไทย (ชื่ออังกฤษ : Effect of Tepoxalin on Fecal Cortisol Concentration in Rabbits after Ovariohysterectomy )

ผู้เขียน:ImgKritkrnda Kiratitana-olan, ImgChatchote Thitaram, ImgPinich Boontong, ImgRaktham Maktrirat, ImgNiyada Thitaram



Determination of the analgesic efficacy of tepoxalin after ovariohysterectomy based on assessment of fecal cortisol cocentration was wtudied in 21 rabbits. Three studied groups ( 7 rabbits/group) consisted of : 1) placebo (oral administration of water 0.1 ml/kg); 2) tepoxalin - treated group I ( 10 mg/kg) ;and 3) tepoxalin - treated group II ( 20 mg/kg as an initial dose, followed by 10 mg/kg after 24 hr). Rabbits received placebo or tepoxalin orally 2 hr before and every 12 hr after surgery for 3 days. Feces were collected and analyzed pre-and post -operation. Te results showed fecal cortisol concentration in tepoxalin-treated group II were significantly lower than other groups. This study indicated that tepoxalin administration twice a day as an initial dose of 20 mg/kg. followed by 10 mg/kg after 24 hr affected the reduction of fecal cortisol concentration reflecting post-operation pain relief in rabbits.

Article Info
วารสาร คณะสัตวแพทยศาสตร์(Journal of Kasetsart Veterinarians), Volume 021, Issue 1, Jan 11 - Apr 11, Page 11 - 20 |  PDF |  Page