Search Result of "Chunxiu Peng"

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Antioxidative effect of large molecular polymeric pigments extracted from Zijuan Pu-erh tea in vitro and in vivo

ผู้แต่ง:ImgQiuping Wang, ImgChunxiu Peng, ImgJiashun Gong, ImgDr.Sarote Sirisansaneeyakul, Professor,




ที่มา:วิทยาสารเกษตรศาสตร์ สาขา วิทยาศาสตร์

หัวเรื่อง:ไม่มีชื่อไทย (ชื่ออังกฤษ : Antioxidative Effect of Large Molecular Polymeric Pigments Extracted from Zijuan Pu-erh Tea In Vitro and In Vivo)

ผู้เขียน:ImgQiuping Wang, ImgChunxiu Peng, ImgJiashun Gong, Imgดร.สาโรจน์ ศิริศันสนียกุล, ศาสตราจารย์



tea was investigated in vitro and in vivo. The results showed that LMPP had signifi cant scavenging activities on the hydroxyl radical and the 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical in vitro and showed strong reducing power. Moreover, the 50% inhibitory concentrations of LMPP for scavenging DPPH radical and hydroxyl radical were 0.217 mg.mL-1 and 0.461 mg.mL-1, respectively. In vivo, the LMPP-treated rat groups showed signifi cantly increased serum superoxide dismutase (SOD) and glutathione peroxidase (GSH-PX) activities, reduced malondialdehyde (MDA) formation, increased nitric oxide (NO) production and signifi cantly decreased rat endothelin-1(ET-1) concentrations compared with those in the hyperlipidemia model group (P < 0.05). The serum SOD and GSH-PX activities and NO concentration were 66.88, 29.09 and 55.11% higher, respectively, whereas, the serum ET-1 and MDA concentrations were 34.62 and 59.11% lower in the high-dose LMPP treatment group (1.215 body weight) than in the hyperlipidemia model group (P < 0.05). These results showed that LMPP has a good antioxidative function and can be considered as a natural antioxidant source.

Article Info
Agriculture and Natural Resources -- formerly Kasetsart Journal (Natural Science), Volume 047, Issue 5, Sep 13 - Oct 13, Page 739 - 747 |  PDF |  Page 



ดร. สาโรจน์ ศิริศันสนียกุล, ศาสตราจารย์

ที่ทำงาน:ภาควิชาเทคโนโลยีชีวภาพ คณะอุตสาหกรรมเกษตร